Shandong Journal of Traditional Chinese Medicine

 

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Journal Title: Shandong Journal of Traditional Chinese Medicine
ISSN：0257-358X
CN：37-1164/R
Sponsors: Shandong Association of Traditional Chinese Medicine; Shandong University of Traditional Chinese Medicine

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2019年07期目次

  • Name,Syndromes and Treatments of Chronic Brain Injury in Traditional Chinese Medicine

    DING Yuanqing;The Affiliated Hospital of Shandong University of Traditional Chinese Medicine;

    According to the attacking and injuring characteristics of chronic brain injury,the author names it "brain injury and spirit weakness disease" in traditional Chinese medicine and makes an initial summary on diagnostic criteria of "brain injury and spirit weakness". With the brain as the main injured region,the key pathogenesis of the disease is kidney deficiency and pathogenic factors accumulation which then causes injury of brains and vital spirit. At the same time,other common pathogenesis includes viscera deficiency,meridians injury,obstruction of blood vessels and stoppage of blood flow. For the excess of pathogenic factors,lingering pathogenic factors in the deficient part,retention of phlegm,turbidity and blood stasis,obstruction of the brain by pathogenic factors,all of them are the sources of it. Although the pathogenesis is complicated,deficiency of the kidney and essence and decline of the brain and marrow are the fundamental causes. In clinical treatment,the disease can be divided into six syndromes and the general treatment principles are as follows:consolidating body resistance by tonifying the kidney essence and generating marrow,treating symptoms by resolving phlegm,promoting blood circulation,removing blood stasis and unblocking meridians,with a supplementary of generating marrow to benefit the brain and spirit. For medicines,kidney-tonifying and skill-strengthening medicine should be used as the main medicine.Besides,medicines for nourishing yin,resolving phlegm,suppressing yang,extinguishing wind,promoting blood circulation and unblocking collaterals also should be taken into consideration.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 147K]

  • Conflicts and Integration among Theories of Five Zang-Viscera,Six Fu-Viscera and Twelve Channels

    LIU Peng;Basic Medical College of Guangzhou University of Chinese Medicine;

    There are conflicts among five Zang-viscera,six Fu-viscera and twelve channels. Five Zang-viscera and six Fu-viscera represent yin and yang respectively and they are the exterior or interior of each other,but the number of five and six does not match obviously. The twelve channels correspond to the zang-fu viscera,but the five Zang-viscera and six Fu-viscera directly add up to eleven,which is obviously not equal to twelve. Therefore,the theory of five Zang-viscera,six Fu-viscera and twelve channels in Huangdi's Internal Classic should have different origins. Firstly,the five Zang-viscera were set up to correspond to the five elements. Secondly,the setting of the six Fu-viscera was not originally intended to correspond to the five Zang-viscera and five elements. Thirdly,the twelve channels were not designed to correspond to the five Zang-viscera,but to transform the five Zang-viscera and integrate the six Fu-viscera according to the criterion of trichotomy of yin and yang. Above all,the editors of Huangdi's Internal Classic took the prevailing yin-yang and five elements doctrine of the Han Dynasty as the standard,reformed and combined them,and realized the integration of academic thoughts of different schools.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 102K]

  • Analysis of Special Medication Drinks in Key to Therapeutics of Children's Diseases

    TIAN Yi;REN Weiming;WU Chengyan;Nanjing University of Chinese Medicine;

    QIAN Yi recorded 120 prescriptions in the last volume of Key to Therapeutics of Children's Diseases. follwing the prescriptions,medication drinks and the way to use them also can be found in several places. This article sorted out these special medication drinks(including traditional chinese medicine decoction,breast milk,wine,special water,etc.) in the book and then summarized their functions and characteristics. The usage characteristics of the special medication drinks were as follows:firstly,for different syndromes,the compatibility is flexible. Secondly,the measures of using medication drinks were suited to different time. Thirdly,protecting spleen and stomach was the focus in using the medication drinks. The combination of prescriptions and medication drinks varied flexibly with disease and syndrome,season,age and constitution of children,which can provide guidance for the pediatric clinical medication and nursing.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 112K]

  • Ideas and Methods of Treating Hepatitis B Virus(HBV)-Related Cirrhosis with Integrated Traditional Chinese and Western Medicine Based on Concept of “Dispelling Pathogenic Factors First”

    LI Lu;HU Dongqing;SUN Jianguang;WANG Lei;Department of Hepatology,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine;

    Hepatitis B virus(HBV)-related cirrhosis is the end-stage of chronic HBV infection. The progress of liver cirrhosis is related to the level of HBV in vivo and long-term effective etiological treatment makes partial regression of liver cirrhosis possible. Antiviral treatment shows the important clinical significance of controlling the etiological factors,which is in line with the therapeutic concept of "removing pathogenic factors to restore health" in traditional Chinese medicine(TCM). According to the theory of TCM epidemic febrile disease,HBV belongs to the category of "latent pathogenic factor" and its nature is dampness-heat epidemic toxin. Dampness-heat epidemic toxin lingering in blood and stagnant heat entering collaterals is the core pathogenesis of HBV-related cirrhosis. From the aspect of combination of disease and syndrome,the treatment emphasizes "dispelling pathogenic factors first" and the basic methods are clearing away heat,detoxifying toxins and removing blood stasis.As a basic prescription,Sanjia Fugan Decoction is added or subtracted according to different conditions,combined with standard anti-HBV treatment. At the same time,Chinese patent drugs for anti-hepatic fibrosis are applied according to syndrome differentiation,in order to block,delay or reverse the progress of liver cirrhosis in time.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 214K]

  • New Ideas of Diagnosis and Treatment of Pulmonary Diseases in Traditional Chinese Medicine Based on Systematic Theory

    LI Peilan;YUAN Kang;LI Kuangyi;CAI Hairong;Guangzhou University of Chinese Medicine;Foshan Hospital of Traditional Chinese Medicine;

    Systematics is a science proposed by QIAN Xuesen to study the general laws of system structure and function. According to the systematics and the diagnosis and treatment theories of pulmonary diseases in The Inner Canon of Huangdi and Treatise on Febrile Diseases,the pulmonary system can be divided into three parts,namely lung defense,lung collaterals and lung viscus. The lung defense is on the surface,so diseases of this part mainly locate in skin,hair and nose,which should be treated with Guizhi Mahuang Geban Decoction to disperse wind and cold mildly. The lung collaterals is a part to connect lung defense with lung viscus and the diseases of this part locate in trachea and bronchus,which should be treated with Xiaoqinglong Decoction,Maxingshigan Decoction or Guizhi Jia Houpo Xingzi Decoction,aiming at warming lung and resolving phlegm,clearing and dispersing lung-heat,descending lung qi,respectively. The lung viscus is the core of pulmonary system and the disease location of this part is the deepest. The diseases of this part can be treated with Zhenwu Decoction to warming lung,benefiting yang and promoting urination.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 142K]

  • Retrospective Analysis of Clinical Literature on Wind-Warm Disease with Lung Heat Treated by Traditional Chinese Medicine

    PENG Kun;SONG Yuanying;YANG Yi;Hubei University of Chinese Medicine;Hubei Provincial Hospital of Traditional Chinese Medicine;

    Objective:To make a retrospective analysis of clinical literature on wind-warm disease with lung heat treated by traditional Chinese medicine(TCM),so as to expound the research status of treatment of wind-warm disease with lung heat by TCM therapy,thus providing data support for further study of wind-warm disease with lung heat. Methods:Related clinical literature on wind-warm disease with lung heat treated by TCM published from January 2001 to June 2017 was searched from Chinese National Knowledge Infrastructure(CNKI),Wanfang Database,VIP Chinese Periodicals Service Platform Database and China Biology Medicine Database to review and analyze the involved drugs,observed objects,syndrome types,observation time,test methods,observation parameters,criterion of curative efficacy,external treatments,clinical pathways,adverse reactions and clinical theories. Results:A total of 121 articles were included and 9644 patients were involved. All the observation objects were patients with wind-warm disease with lung heat chosen by a strict criteria. The general test methods were mutual control and self control. The criterion of curative efficacy included improvements of symptom scores,clinical inflammatory parameters and various biochemical paratemers. There were 41 kinds of drugs and 11 kinds of TCM syndrome types. The clinical observation or test time was 7 to 10 days and the observation parameters mainly included clinical symptoms and laboratory examination parameters. For the curative efficacy,the improvement rate of TCM symptoms and syndromes obtained by TCM internal treatment was not less than 70% and the external treatment was able to shorten the course of disease and improve part of the patients' symptoms. The implementation of clinical pathway could improve clinical efficacy and reduce the costs of diagnosis and treatment. Some patients treated by TCM suffered from adverse reactions. Clinical theoretical studies summarized its etiology,pathogenesis and medication characteristics. Conclusions:The exact efficacy of TCM on the treatment of wind-warm disease with lung heat has been confirmed. TCM has certain advantages in improving clinical symptoms,shortening the course of disease,reducing complications and medical costs,but the stability of efficacy and mechanism of TCM should be further clarified.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 373K]

  • Clinical Study of Treating Type 2 Diabetes Mellitus of Shaoyang Disorder Syndrome by Modified Xiaochaihu Decoction Combined with Western Medicine

    CUI Yan;Endocrine Department,Ankang Hospital of Traditional Chinese Medicine;

    Objective:To study the effects of modified Xiaochaihu Decoction combined with western medicine on clinical symptoms,body mass index(BMI),blood glucose,blood lipid and inflammatory factors of patients with type 2 diabetes mellitus(T2 DM) of Shaoyang disorder syndrome. Methods:A total of 180 patients with T2 DM of Shaoyang disorder syndrome were divided into observation group and control group according to the time sequence of seeing doctor,with 90 cases in each group. Because 8 patients withdrew from the study,finally there were 172 cases completed this study,with 87 cases in the observation group and 85 cases in the control group. Health education,diet control and regular exercise were carried out in both groups. The control group was treated with metformin hydrochloride tables and detinsulin.On the basis of the control group,the observation group was treated with modified Xiaochaihu Decoction. For both groups,1 treatment course lasted for 3 months and 1 course of treatment was given to them.After treatment,the patients were followed for 6 months. Before treatment,after treatment and 6 months after treatment,indicators of the two groups including classification and quantification of traditional Chinese medicine symptoms,BMI,changes of blood glucose and lipid,inflammatory factors,levels of serum Hcy and fibrinogen,life quality were compared. Results:After treatment and 6 months after treatment,indicators of the two groups such as the classification and quantification of traditional Chinese medicine symptoms,BMI,blood glucose and lipid,inflammatory factors,levels of serum Hcy and fibrinogen,life quality were all improved,and the improvements of the observation group were better than those of the control group. The differences were statistically significant(P<0.05). Conclusions:Modified Xiaochaihu Decoction combined with western medicine treatment can significantly improve the clinical symptoms and islet function of patients with T2 MD of Shaoyang disorder syndrome,reduce the expression of inflammatory factors,and improve their life quality.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 270K]

  • Analysis of Laws of Medicine Application in Traditional Chinese Medicine Health Care Foods for Improving Sleep Quality Based on Data Mining

    QI Biao;ZHANG Mingzhe;MENG Yumei;HUANG Dali;FU Rong;WANG Feifei;HU Xiaoqin;DENG Jia-gang;DU Zhengcai;Pharmacy College of Guangxi University of Chinese Medicine;Science Experiment Center of Guangxi University of Chinese Medicine;

    Objective:To analyze the laws of medicine application in traditional Chinese medicine(TCM)health care foods for improving sleep quality,so as to provide reference for research and development of related products. Methods:TCM heath care foods which were examined and approved after December12,1997 were searched from the official website of China Food and Drug Administration(CFDA). Excel2010 was used to establish one general database and seven sub-database(TCM sub-database,medicine property sub-database,medicine taste sub-database,meridian tropism sub-database,effect sub-database,medicine pair sub-database,triple-hybrid medicine sub-database)about TCM materials in the health care foods. Then frequency analysis was conducted on data from the seven sub-databases and the medicines whose using frequency is more than 1% were introduced into SPSS24 software,so as to proceed clustering analysis of the property,taste,channel tropism and major effects of the TCM by the hierarchical clustering method. Results:A total of 539 TCM heath care foods for improving sleep quality were searched out from the CFDA. After screened by the inclusion and exclusion criteria,354 foods were finally included in the study. The top 3 medicines with the highest frequency were Suanzaoren(Ziziphy Spinosae Semen),Wuweizi(Schisandrae Chinensis Fructus) and Fuling(Poria). From the perspective of effect,the top 3 kinds of medicine with the highest frequency were tonifying medicines,tranquilizing medicines and liver-pacifying and wind-extinguishing medicines. The high-frequency medicine pairs and triple-hybrid medicines included Suanzaoren + Wuweizi,Suanzaoren + Fuling,Suanzaoren + Wuweizi + Fuling. The medicines were mainly mild and their tastes were mainly sweet,bitter,sour and pungent. For the meridian tropism,the main meridian were liver,heart,spleen and kidney. By clustering analysis,5 core groups of medicines were formulated. Conclusions:The main tastes and property of medicines in TCM health care foods for improving sleep quality were sweet and mild,sweet and warm(hot),sweet and cold(cool). The medicines mainly acted on liver meridian,heart meridian,spleen meridian and kidney meridian.The 21 high-frequency medicines obtained from the data analysis could be used as core materials for health care foods for improving sleep quality,especially the first 6 shall be put more efforts to research and develop. In medicine compatibility,blood-nourishing and tranquilizing medicines has well compatibility with tonifying medicines and astringent medicines,as well as with liver-pacifying and wind-extinguishing medicines,and dampness-draining diuretic medicines. The treatment principles are as follows:Patients with deficiency syndrome could be treated by tonifying qi,nourishing blood and reinforcing yin. Patients with blood stasis,phlegm turbidity,hyperactivity of yang and exuberant fire of heart and liver could be treated by invigorating circulation of blood,draining dampness,pacifying liver and suppressing yang,clearing away exuberant fire of heart and liver. On the basis of the above treatments,it shall be cooperated with blood-nourishing tranquilizing medicines or mind-tranquilizing medicines.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 194K]

  • Clinical Study of Sling Exercise Training Combined with Shock Wave Therapy in Treatment of Ⅰ Stage Shoulder-Hand Syndrome after Stroke

    ZHANG Jiapeng;LI Li;XU Qiangqiang;LI Fei;WANG Ning;Rehabilitation College of Shandong University of Traditional Chinese Medicine;The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine;

    Objective:To observe the curative efficacy of sling exercise training(SET) combined with shock wave therapy on pain,shoulder function and upper limb motor function of patients with Ⅰ stage shoulder-Hand Syndrome(SHS) after stroke. Methods:A total of 90 patients withⅠ stage SHS after stroke were divided into three groups(group A,group B and group C) according to the random number table. Besides general rehabilitation therapy applied in all the three groups,group A was only treated with SET,group B was only treated with shock wave and group C was treated with SET combined with shock wave. For all the three groups,one treatment course lasted for two weeks and two courses of treatments were given to them.Before and after treatment,the pain,shoulder function and upper limb motor function of patients in all the three groups were evaluated by visual analogue scale(VAS),Constant-Murley shoulder function evaluation method and Fugl-Meyer assessment(FMA) scale. The curative efficacy of all the three groups were compared. Results:The total effective rate of group C was 96.55% which was higher than that of group A and group B,and the differences were statistically significant(P<0.05). The VAS score,ConstantMurley shoulder function score and FMA upper limb motor function score of patients in all the three groups were improved after treatment. The improvements of group C were better than those of group A and group B and the differences were statistically significant(P<0.05). The VAS score of Group B was lower than that of group A,whereas its FMA upper limb motor function score was higher than that of group A.The differences were statistically significant(P<0.05). For the shoulder function score,the differences between group A and group B were not statistically significant(P> 0.05). Conclusion:SET combined with shock wave therapy has obvious curative efficacy on patients with Ⅰ stage SHS after stroke.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 201K]

  • Analysis of Laws of Acupoint Selection in Treatment of Cough Variant Asthma by Herbal Plaster on Acupoints Based on Data Mining

    WANG Panpan;YIN Weihao;SHI Chen;QU Baoping;WANG Mengmeng;LIU Ying;College of Acupuncture and Tuina,Shandong University of Traditional Chinese Medicine;Linyi Hospital of Traditional Chinese Medicine;

    Objective:Using data mining techniques to analyze and evaluate laws of acupoints selection in treatment of cough variant asthma by herbal plaster on acupoints. Methods:Related literature on treatment of cough variant asthma by herbal plaster on acupoints published from January 2002 to October 2017 were obtained through searching Chinese National Knowledge Infrastructure(CNKI) and Wanfang Database. The search keywords were "cough variant asthma""herbal plaster on acupoints""plaster" and "acupoints". When the literature was searched,the keyword "cough variant asthma" was combined with "herbal plaster on acupoints""plaster" and "acupoints" respectively.Then screened out the qualified literature according to the inclusion and exclusion criteria. Finally,the acupoints that were used in the qualified literature were given descriptive analysis and cluster analysis.Results:A total of 40 articles with 23 acupoints were included. The descriptive analysis shows that the most frequently used acupoint was Feishu(BL13) and the bladder meridian was the one with most selected acupoints. And the commonly used acupoints are mainly distributed on the upper back,chest and abdomen.The cluster analysis shows that the commonly used acupoints can be divided into three categories. The first category was Gaohuang(BL43)-Dazhui(DU14)-Pishu(BL20)-Shenshu(BL23)-Xinshu(BL15),the second category was Dingchuan(EX-B1)-Danzhong(RN17)-Geshu(BL17) and the third category was Feishu(BL13)-Tiantu(RN22). Among the three categories,the second category can be further divided into two categories.One of the subcategories was Dingchuan-Danzhong and the other was Geshu. Conclusions:In treatment of cough variant asthma by herbal plaster on acupoints,there were some basic acupionts and other acupoints were selected according to syndrome differentiation. In addition,some methods such as regulating qi movement,promoting the recovery of lung function,regulating liver and spleen and tonifying liver and kidney ran through the treatments.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 403K]

  • Expressions of NGAL,KIM 1 and Cys C in Patients with Sepsis-Induced Acute Kidney Injury Treated by CRRT Combined with Huoxue Jiedu Yiqi Decoction and Their Prognostic Value

    LI Zhaochun;Weifang Hospital of Traditional Chinese Medicine;

    Objective:To observe the expressions of neutrophil gelatinase-associated lipocalin(NGAL),kidney injury molecule 1(KIM 1) and cystatin C(Cys C) in patients with sepsis-induced acute kidney injury(AKI) treated by continuous renal replacement therapy(CRRT) combined with Huoxue Jiedu Yiqi Decoction and analyze their prognostic value. Methods:A total of 120 patients with sepsis were divided into AKI group(62 cases with sepsis-induced AKI) and non-AKI group(58 cases without sepsis-induced AKI).The AKI group was treated with CRRT combined with Huoxue Jiedu Yiqi Decoction and the non-AKI group was treated with conventional basic therapy. After treatment,routine parameters of the two groups such as acute physiology and chronic health evaluation Ⅱ(APACHE Ⅱ) score,sequential organ failure assessment(SOFA) score,brain natriuretic peptide(BNP),oxygenation index,ICU retention time,average length of hospital stay and so on were observed. The levels of serum creatinine(SCr),NGAL,KIM 1 and Cys C of the two groups were observed at the 0 th,6 th,12 th,24 th and 48 th hour in ICU. The correlation between levels of Cys C,NGAL,KIM 1 and SCr level,SOFA score,APACHE Ⅱ score of the two groups was analyzed before and after treatment. After treatment,the patients were followed for 28 days to record the prognosis.At the same time,the value of NGAL,KIM 1 and Cys C in predicting kidney function and death rate of the patients were analyzed. Results:After treatment,the differences of APACHE Ⅱ scores,SOFA scores,BNP,oxygenation index,ICU retention time and average length of hospital stay between the two groups were statistically significant(P<0.05). In the AKI group,the levels of SCr,Cys C reached a peak value at the12 th hour in ICU,the level of KIM 1 reached a peak value at the 24 th hour in ICU and the level of NGAL reached a peak value at the 0 th hour in ICU. After treatment,all the above parameters of the AKI group were decreased and the differences of these parameters between the two groups were statistically significant(P<0.05). The NGAL level,Cys C level and APACIIE Ⅱ scores were positively correlated. In the AKI group,18 patients(29.03%) died shortly after the treatment. The major causes of death were organ failure,severe infection or respiratory failure. Among the survived 44 cases,21 cases(47.73%) had renal function recovery and were out of dialysis,but the other 23 cases(52.27%) had kidney loss. Conclusions:CRRT therapy combined with Huoxue Jiedu Yiqi Decoction can protect the renal function of patients with sepsis-induced AKI by reducing the level of Cys C and regulating the expressions of KIM 1 and NGAL.The levels of NGAL,KIM 1 and Cys C can be used as independent prognostic parameters for the patients.The predictive value of NGAL and Cys C is high,but the predictive value of KIM 1 is low.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 686K]

  • Clinical Study of Cooling Blood and Clearing Heat Method Combined with Propafenone Hydrochlorideon for Treatment of Paroxysmal Atrial Fibrillation of QI and Yin Deficiency Syndrome

    SONG Chunxue;ZOU Jihong;WANG Tingting;Department of Cardiovascular Disease,the Fourth Affiliated Hospital of Liaoning University of Traditional Chinese Medicine;

    Objective:To study the effect of cooling blood and clearing heat method combined with propafenone hydrochloride on paroxysmal atrial fibrillation of qi and yin deficiency syndrome. Methods:A total of 90 patients with paroxysmal atrial fibrillation of qi and yin deficiency syndrome were divided into observation group and control group randomly,with 45 cases in each group. The observation group was treated with cooling blood and clearing heat decocttion combined with propafenone hydrochloride,while the control group was only treated with propafenone hydrochloride. The curative effect and atrial fibrillation of the two groups were compared before and after treatment. The changes of electrocardiogram parameters such as maximum P wave time limit(Pmax),minimum P wave time limit(Pmin),P wave dispersion(Pdis) and the average heart rate of the two groups were recorded. Results:The total effective rate of the observation group was higher than that of the control group and the difference was statistically significant(P<0.05). After treatment,the frequency and duration of atrial fibrillation in the two groups were less than those before treatment and the differences were statistically significant(P<0.05). The frequency and duration of atrial fibrillation in the observation group after treatment were less than those in the control group and the differences were statistically significant(P<0.05). After treatment,the Pmax,Pdisand average heart rate of the two groups were lower than those before treatment and the differences were statistically significant(P<0.05). The Pmax,Pdisand average heart rate in the observation group after treatment were lower than those in the control group and the differences were statistically significant(P<0.05). Conclusion:The cooling blood and clearing heat method combined with propafenone hydrochloride is effective in the treatment of paroxysmal atrial fibrillation of qi and yin deficiency syndrome,which is helpful to improve the clinical symptoms and electrocardiogram manifestation of the patients.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 209K]

  • Effect of Baduanjin's Third Part Combined with Conventional Balance Training on Balance Function of Patients with Cerebral Stroke

    DING Yi;GUO Chenchen;WANG Ning;NIU Xingchen;LI Li;Shandong University of Traditional Chinese Medicine;The Second Affiliated Hospital of Shandong University of Traditional Chinese Medicine;

    Objective:To observe the clinical effect of Baduanjin's third part combined with conventional balance training on balance dysfunction of patients with cerebral stroke. Methods:A total of 120 patients were divided into treatment group and control group by the random number table,with 60 cases in each group. Both groups were rehabilitated on the basis of basic medical treatment. The control group was only given conventional balance training. The treatment group was given conventional balance training combined with Baduanjin's third part training. For both the two groups,a course of treatment lasted for 5 days and a total of four courses of treatment were given to them. Before and after treatment,the Berg balance scale(BBS) and the Fugl-Meyer Balance(FMB) Scale were used to assess the patient's balance ability. Rehabilitative ultrasound imaging was used to detect the thickness of transverse abdominal muscle and multifidus muscle in patients' core muscle groups,so as to evaluate the muscle improvement of the patients. Results:Compared with before treatment,the BBS score,FMB score and muscle thickness of the two groups were significantly improved after treatment and the differences were statistically significant(P<0.05). The improvements of the treatment group was better than those of the control group and the differences were statistically significant(P<0.05). Conclusion:The combination of Baduanjin's third part and the conventional balance training can significantly improve the balance function of patients with cerebral stroke. Its effect is better than that of only conventional balance training.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 207K]

  • Experience of ZHANG Yongchen in Differentiation and Treatment of Tinnitus Cerebri with Acupuncture-Dominated Methods

    GUO Chenchen;DING Yi;CUI Xiang;ZHANG Yongchen;Acupuncture and Tuina College of Shandong University of Traditional Chinese Medicine;Rehabilitation College of Shandong University of Traditional Chinese Medicine;

    Professor ZHANG Yongchen believes the location of tinnitus cerebri is in the brain. The deficiency of kidney essence and insufficiency of marrow sea is the fundamental pathogenesis. Clinically,it can be divided into four types:deficiency of kidney essence,deficiency of qi and blood,depressed liver qi transforming into fire,phlegm clouding the clear orifices. For the deficiency syndrome,the principle of treatment is supplementing essence and morrow,replenishing qi and blood. For the excess syndrome,the principle of treatment is soothing the liver and regulating qi,tonifying the spleen to resolve phlegm. In treatment,the effect of basic acupuncture prescription combined with navel therapy,cupping,auricular acupoints and other external treatment is remarkable. Addition or subtraction of the above methods is regulated according to different syndrome types. One example is listed to show the efficacy.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 173K]

  • Experience of Professor TANG Nong in Treating Recurrent Oral Ulcer in Elderly Patients by Strengthening Yang Method

    QIN Lyuxing;ZHOU Xiaoling;LI Junhong;HUANG Lan;MO Qiulan;ZHENG Pan;MO Xueni;Gou Yao;TANG Nong;Liuzhou Hospital of Traditional Chinese Medicine;The First Affiliated Hospital of Guangxi University of Chinese Medicine;Guangxi University of Chinese Medicine;

    Guided by the thought of yang in The Inner Canon of Huangdi and the strengthening yang theories of ZHENG Qin'an,Professor TANG Nong believes that recurrent oral ulcers in elderly patients are mostly caused by yang deficiency. For elderly patients,because their yang qi is deficient,the cold pathogen is relatively strong. The cold pathogen invades the position of yang,making the original "yang in the interior and yin in the exterior" structure transforms to "yin in the interior and yang in the exterior". The clinical characteristics often manifested as "heat in the upper and cold in the lower,cold in the interior and heat in the exterior". Therefore,strengthening yang is vital in the treatment,restraining the yang in the exterior and warmming the yin in the interior,so as to making yang come back to its original position and the abnormal "yin in the interior and yang in the exterior" structure returns to "yang in the interior and yin in the exterior". Then the body can reach a harmonious state of yin-yang balance and have self-healing capability. According to the different stages of the disease,Guizhi Decoction,Qianyang Fengsui Pill and Buyi Decoction are used in the treatment to get good effect. One proved case is listed to show the efficacy.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 135K]

  • Professor WU Xinhua's Experience in Treating Lichen Sclerosus of Vulva

    JU Hongmei;CUI Xinhong;WU Xinhua;Department of Gynaecology,the Affiliated Hospital of Shandong University of Traditional Chinese Medicine;Department of Obstetrics and Gynecology,South Campus of the 960th Hospital of the People's Liberation Army;

    In clinical treatment of lichen sclerosus of vulva which is caused by downward flow of dampness-heat from the liver meridian combined with deficiency of spleen and kidney yang,Professor WU often uses methods of soothing liver,clearing heat,drying dampness,warming kidney and invigorating spleen. The internal and external application of self-made liver-clearing and soothing prescription,heat-clearing and dampness-draining prescription and prescription for leukoplakia vulvae has achieved good clinical effect. Two proved cases are listed in the article to show the efficacy.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 103K]

  • Study on Active Ingredients of Jianghuang(Curcumae Longae Rhizoma) against Prostatic Hyperplasia

    LIU Li;ZHANG Lu;WANG Kaiyan;ZHANG Zhenzhen;XU Guihong;LIN Guitao;Shandong University of Traditional Chinese Medicine;Shandong University of Arts;Qihe County People's Hospital;

    Objective:To observe the inhibitory effect of 75% ethanol extract of Jianghuang(Curcumae Longae Rhizoma) on prostatic hyperplasia of benign prostatic hyperplasia model mice and to explore the active ingredients of Jianghuang in inhibiting prostatic hyperplasia. Methods:The content of curcumin in different solvent extracts of Jianghuang extracted by 75% ethanol was determined and the effect of different solvent extracts on the prostate coefficient of the model mice with benign prostatic hyperplasia was observed. Results:Both ether extract with the highest curcumin content and n-butanol extract with the lowest curcumin content can reduce the prostate coefficient,and there was no significant difference between the effect of the two extracts. Conclusions:The 75%ethanol extract of Jianghuang has a good curative effect on benign prostatic hyperplasia. Besides curcumin,other ingredients have similar inhibitory effect on prostatic hyperplasia with curcumin.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 195K]

  • Study on Mechanism of Zuojin Pill Based on Network Pharmacology

    YANG Shuhui;TAN Meiao;KUANG Weihong;LIU Xiaoman;The First Clinical College of Guangzhou University of Chinese Medicine;The First Affiliated Hospital of Guangzhou University of Chinese Medicine;

    Objective:To explore the mechanism of Zuojin Pill. Methods:First,through traditional Chinese medicine systems pharmacology database and analysis platform,protein database and disease database,the effective compounds,related target proteins and target genes of Zuojin Pill were inquired. Then,the component-target,target-disease and protein interaction network diagram were constructed. The gene ontology-biology process(GO-BP) and Kyoto encyclopedia of genes and genomes(KEGG) pathway analysis of target proteins were performed and the diagram was made. Results:A total of 42 effective compounds including quercetin and berberine were obtained. After screened by molecular online docking platform,214 targets,622 related diseases and 10 hub proteins,including interleukin-6,interleukin-10 and matrix metalloproteinase-9 were obtained. The GO-BP enrichment was related to biological processes such as transcriptional regulation,signal pathway,substance reaction and apoptosis. The KEGG analysis included cancer,liver disease,endocrine and other related signal pathways. Conclusion:The targets of Zuojin Pill are related to cancer,liver disease,metabolic disease,cardiovascular disease,inflammatory disease and other diseases,especially cancer.

    2019 07 v.38;No.381 [Abstract][OnlineView][Download 3284K]