乳腺癌围化疗期的中医药干预策略探讨Exploring Traditional Chinese Medicine Intervention Strategy During Peri-chemotherapy Period of Breast Cancer
崔莎莎,姜翠红
CUI Shasha,JIANG Cuihong
摘要(Abstract):
化疗在乳腺癌治疗中占重要地位,但易损伤人体正气,在围化疗期进行中医药干预能够顾护正气,减毒增效。患者体质不同,对化疗的耐受性有异,故化疗前宜辨体论治以求本,提高患者对化疗的耐受性;不同的肿瘤类型化疗方案有所不同,化疗中应辨病与辨证相结合,辨病以制定化疗方案,再针对不同方案中药物产生的不良反应辨证论治;化疗后患者正气尚未完全恢复,应重点扶助正气、改善患者体质、清除余毒,防止复发、转移。
Chemotherapy plays a vital role in the treatment of breast cancer,but it usually damages the healthy qi of patients. Traditional Chinese medicine(TCM) intervention in the peri-chemotherapy period could protect healthy qi and reduce toxicity. Patients with different constitutions have different tolerance to chemotherapy. Therefore,it is advisable to differentiate the body constitution before chemotherapy in order to treat the root and improve the patient's tolerance to chemotherapy. Chemotherapy regimens vary according to tumor types. Disease differentiation and syndrome differentiation should be combined during chemotherapy.Disease differentiation should be used to establish chemotherapy regimens,and adverse reactions caused by drugs in different regimens should be treated based on syndrome differentiation. After chemotherapy,healthy qi of patient is not fully recovered,and therefore strengthening healthy qi and improving body constitution should be emphasized to remove residual toxin,and prevent recurrence and metastasis.
关键词(KeyWords):
乳腺癌;围化疗期;辨体论治;病证结合;扶正解毒
breast cancer;peri-chemotherapy period;treatment based on constitution differentiation;combination of disease and syndrome;strengthening healthy qi and detoxicating
基金项目(Foundation): 国家自然科学基金项目(编号:81703918);; 中国中医科学院广安门医院南区院级课题(编号:Y2019-04)
作者(Author):
崔莎莎,姜翠红
CUI Shasha,JIANG Cuihong
DOI: 10.16295/j.cnki.0257-358x.2022.07.002
参考文献(References):
- [1]陈前军,裴晓华.早期乳腺癌中医辨证内治专家共识[J].现代中医临床,2020,27(3):5-8.
- [2]李慧,李达.秉承李达和血法经验探索中医药介入血液肿瘤围化疗期治疗思路[J].中华中医药杂志,2019,34(7):3115-3118.
- [3]张冬妮,张秀丽,卢雯平.“三辨”论治乳腺癌[J].世界中医药,2020,15(4):617-622.
- [4]吴清清,钱铃铃,陈小燕,等.基于“因质施护”中医个性化优质护理肿瘤化疗消化道反应[J].南通大学学报(医学版),2020,40(6):561-563.
- [5]庞博,姜晓晨,朴炳奎,等.肿瘤辨病论治临床思维方法探讨[J].北京中医药,2020,39(5):397-401.
- [6]崔莎莎,卢雯平.乳腺癌“两全”模式下中医干预策略[J].北京中医药,2020,39(10):1018-1021.
- [7]霍斌.肿瘤化疗后胃肠道反应的中医证治及用药规律探讨[J].内蒙古中医药,2019,38(7):133-134.
- [8]冯蓓蓓,张丹.中医药治疗化疗后骨髓抑制研究进展[J].山东中医药大学学报,2017,41(3):290-293.
- [9]林辉,周鹏.生血宝合剂对乳腺癌化疗骨髓抑制的疗效观察[J].现代实用医学,2018,30(9):1152-1153.
- [10]宋鑫,凌婉雯,黄佩茹,等.曹勇自拟固脱生发汤防治肿瘤化疗脱发[J].中医肿瘤学杂志,2020,2(2):79-83.
- [11]卢雯平,陈长怀,花宝金,等.乳腺癌的中医治疗思路及方法[J].中国肿瘤,2003,12(6):331-333.
- [12]李彦彬,邓秀婷,罗姮,等.中药三七与桑葚抗氧化作用的对比研究[J].现代中西医结合杂志,2014,23(8):822-823.
- [13]陈红.中医药防治乳腺癌蒽环类化疗药物致心脏毒性疗效的Meta分析[D].沈阳:辽宁中医药大学,2017.
- [14]刘杰,罗莉,余婷,等.对化疗诱导心脏毒性的中医学认识与辨治探讨[J].山东中医杂志,2020,39(12):1291-1294.
- [15]梁慧,王云启,李玉明,等.中药减轻乳腺癌术后含蒽环类药物辅助化疗心脏毒性的临床研究[J].四川中医,2013,31(6):83-85.
- [16]周倩倩,黄力.人参药物后适应在心肌缺血再灌注损伤中的保护作用[J].中国中医药信息杂志,2011,18(5):107-110.
- [17]黄光辉,孙连娜.麦冬多糖的研究进展[J].现代药物与临床,2012,27(5):523-529.
- [18]王怡,高秀梅,邢永发,等.丹参酚酸B、丹参酮治疗心血管疾病的药理学研究进展[J].上海中医药杂志,2010,44(7):82-87.
- [19]周海燕.浅析甘松在心系疾病治疗中的应用[J].山东医学高等专科学校学报,2018,40(1):76-78.
- [20] CRAIG C D,MONK B J,FARLEY J H,et al. Cognitive impairment in gynecologic cancers:a systematic review of current approaches to diagnosis and treatment[J].Support Care Cancer,2014,22(1):279-287.
- [21]卢超,陈淼,邹善林.针灸治疗“化疗脑”的理论基础与选穴思路[J].中国针灸,2018,38(12):1331-1334.
- [22]高雅静,卢雯平,邱瑞瑾.疏肝益肾方加减治疗乳腺癌化疗脑142例[J].中国中医药信息杂志,2013,20(9):70-71.
- [23]李洪兵.何首乌的现代药理学研究综述[J].云南中医中药杂志,2012,23(6):72-76.
- [24]冯彦.丹参的现代药理研究及临床应用[J].中医临床研究,2017,9(30):46-47.
- [25]李冀,李想,高彦宇,等.中药石菖蒲研究进展[J].辽宁中医药大学学报,2019,21(10):13-17.